Phosphorylation of the Menin Tumor Suppressor Protein on Serine 543 and Serine 583
نویسندگان
چکیده
منابع مشابه
Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583.
Multiple endocrine neoplasia type 1 (MEN-1) is a heritable syndrome typified by tumors in multiple endocrine organs, including the pituitary, parathyroids, and pancreatic islets. MEN-1 is attributable to mutations in the MEN1 tumor-suppressor gene that encodes the menin protein. Recent studies have implicated menin in transcriptional regulation and in covalent histone modification; however, lit...
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ژورنال
عنوان ژورنال: Molecular Cancer Research
سال: 2006
ISSN: 1541-7786,1557-3125
DOI: 10.1158/1541-7786.mcr-06-0123